University at Buffalo 2-3 credits Biochemistry
This course introduces students to the theory and practice of biophysical methods in use in the Jacobs School of Medicine and Biomedical Sciences to probe the protein and nucleic acid conformational and energy landscapes in relation to function. Methods covered include isothermal titration calorimetry, bilayer interferometry, fluorescence resonance energy transfer, single molecule techniques like atomic force microscopy and optical tweezers, light scattering, total internal reflection microscopy, and electron and nuclear magnetic resonance. Class projects involve both written and oral reports. The third credit hour is given to students who elect to prepare an end-of-course research report.
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